Brain network changes and memory decline in aging

Changes in Brain Network Efficiency and Working Memory Performance in Aging

Working memory is a complex psychological construct referring to the temporary storage and active processing of information. We used functional connectivity brain network metrics quantifying local and global efficiency of information transfer for predicting individual variability in working memory performance on an n-back task in both young (n = 14) and older (n = 15) adults. Individual differe...

Autobiographical memory and aging

Autobiographical memory, or memory for personal experiences, allows individuals to define themselves and construct a meaningful life story. Current research aims to review the definition and theories of autobiographies memory and how it usually changes or abnormally in older adults. Base on studies, as we grow older autobiographical memory drops off, also semantic memory changes a little or som...

Patterns of brain atrophy associated with episodic memory and semantic fluency decline in aging

The cerebral substratum of age-related cognitive decline was evaluated in an elderly-cohort followed for 12 years (n=306). Participants, free of dementia, received neuropsychological assessments every two years and an MRI exam at baseline and four years later. Cognitive decline was evaluated on two broadly used tests to detect dementia: the Free and Cued Selective Reminding Test (FCSRT), a verb...

Correction: Patterns of brain atrophy associated with episodic memory and semantic fluency decline in aging

Memory aging and brain maintenance

Episodic memory and working memory decline with advancing age. Nevertheless, large-scale population-based studies document well-preserved memory functioning in some older individuals. The influential ‘reserve’ notion holds that individual differences in brain characteristics or in the manner people process tasks allow some individuals to cope better than others with brain pathology and hence sh...